319 research outputs found

    Examining the Relationship between Emotion Perception and Bullying: A Proposal

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    Bullying and aggressive behaviors have adverse effects on many children. Violent behavior among children occurs most commonly in the school setting and may lead to negative emotional outcomes later in life (Kub & Feldman, 2015). According to a study conducted by Baroncelli et al. (2014), boys who have been found to be high in aggression have a difficult time perceiving relevant social cues such as fear and anger. However, boys were prone to frequently identify happiness and fear in faces when a different emotion was expressed. For girls, Baroncelli and colleagues did not find any significant relationships. The purpose of this paper was to conceptually replicate the research of Baroncelli et al. (2014), which was originally done in Italy. For my study, I plan on using children in the United States to determine if the ability to perceive emotion predicts aggression. Participants will be recruited from Hyde Park Middle School in Las Vegas, Nevada and will consist of approximately 1,100 male and female students. The Aggression Scale (Orpinas & Frankowski, 2001) and the Diagnostic Analysis of Nonverbal Accuracy –2 (DANVA2; Nowicki, 2013; Nowicki & Duke, 1994) will be completed online and will take approximately 30 minutes to complete. In order to determine if there is a relationship between aggression and emotion perception, I will calculate the correlation between the DANVA and the Aggression Scale

    Quality of Peer Relationships Among Children with Selective Mutism

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    The current study examined the quality of peer relationships among children with selective mutism. Previous research suggests that children who are selectively mute have difficulty making friends and have poor outcomes in treatment. Participants were derived from the UNLV Child School Refusal and Anxiety Disorders Clinic. An initial assessment was conducted by the Clinic therapist. The study utilized a demographic form, the Child Behavior Checklist, and the Anxiety Disorders Interview Schedule—Parent Version. The current study found that children who are selectively mute ranged in the quality of friendships, and this knowledge may be used to help treatment outcome

    McNair Research Journal - Summer 2015

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    Journal articles based on research conducted by undergraduate students in the McNair Scholars Program Table of Contents Biography of Dr. Ronald E. McNair Statements: Dr. Neal J. Smatresk, UNLV President Dr. Juanita P. Fain, Vice President of Student Affairs Dr. William W. Sullivan, Associate Vice President for Retention and Outreach Mr. Keith Rogers, Deputy Executive Director of the Center for Academic Enrichment and Outreach McNair Scholars Institute Staf

    Time to treatment with bridging intravenous alteplase before endovascular treatment:subanalysis of the randomized controlled SWIFT-DIRECT trial.

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    BACKGROUND We hypothesized that treatment delays might be an effect modifier regarding risks and benefits of intravenous thrombolysis (IVT) before mechanical thrombectomy (MT). METHODS We used the dataset of the SWIFT-DIRECT trial, which randomized 408 patients to IVT+MT or MT alone. Potential interactions between assignment to IVT+MT and expected time from onset-to-needle (OTN) as well as expected time from door-to-needle (DTN) were included in regression models. The primary outcome was functional independence (modified Rankin Scale (mRS) 0-2) at 3 months. Secondary outcomes included mRS shift, mortality, recanalization rates, and (symptomatic) intracranial hemorrhage at 24 hours. RESULTS We included 408 patients (IVT+MT 207, MT 201, median age 72 years (IQR 64-81), 209 (51.2%) female). The expected median OTN and DTN were 142 min and 54 min in the IVT+MT group and 129 min and 51 min in the MT alone group. Overall, there was no significant interaction between OTN and bridging IVT assignment regarding either the functional (adjusted OR (aOR) 0.76, 95% CI 0.45 to 1.30) and safety outcomes or the recanalization rates. Analysis of in-hospital delays showed no significant interaction between DTN and bridging IVT assignment regarding the dichotomized functional outcome (aOR 0.48, 95% CI 0.14 to 1.62), but the shift and mortality analyses suggested a greater benefit of IVT when in-hospital delays were short. CONCLUSIONS We found no evidence that the effect of bridging IVT on functional independence is modified by overall or in-hospital treatment delays. Considering its low power, this subgroup analysis could have missed a clinically important effect, and exploratory analysis of secondary clinical outcomes indicated a potentially favorable effect of IVT with shorter in-hospital delays. Heterogeneity of the IVT effect size before MT should be further analyzed in individual patient meta-analysis of comparable trials. TRIAL REGISTRATION NUMBER URL: https://www. CLINICALTRIALS gov ; Unique identifier: NCT03192332

    Second intravenous immunoglobulin dose in patients with Guillain-Barre syndrome with poor prognosis (SID-GBS):a double-blind, randomised, placebo-controlled trial

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    Background Treatment with one standard dose (2 g/kg) of intravenous immunoglobulin is insufficient in a proportion of patients with severe Guillain-Barre syndrome. Worldwide, around 25% of patients severely affected with the syndrome are given a second intravenous immunoglobulin dose (SID), although it has not been proven effective. We aimed to investigate whether a SID is effective in patients with Guillain-Barre syndrome with a predicted poor outcome. Methods In this randomised, double-blind, placebo-controlled trial (SID-GBS), we included patients (>= 12 years) with Guillain-Barre syndrome admitted to one of 59 participating hospitals in the Netherlands. Patients were included on the first day of standard intravenous immunoglobulin treatment (2 g/kg over 5 days). Only patients with a poor prognosis (score of >= 6) according to the modified Erasmus Guillain-Barre syndrome Outcome Score were randomly assigned, via block randomisation stratified by centre, to SID (2 g/kg over 5 days) or to placebo, 7-9 days after inclusion. Patients, outcome adjudicators, monitors, and the steering committee were masked to treatment allocation. The primary outcome measure was the Guillain-Barre syndrome disability score 4 weeks after inclusion. All patients in whom allocated trial medication was started were included in the modified intention-to-treat analysis. Findings Between Feb 16, 2010, and June 5, 2018, 327 of 339 patients assessed for eligibility were included. 112 had a poor prognosis. Of those, 93 patients with a poor prognosis were included in the modified intention-to-treat analysis: 49 (53%) received SID and 44 (47%) received placebo. The adjusted common odds ratio for improvement on the Guillain-Barre syndrome disability score at 4 weeks was 1.4 (95% CI 0.6-3.3; p=0.45). Patients given SID had more serious adverse events (35% vs 16% in the first 30 days), including thromboembolic events, than those in the placebo group. Four patients died in the intervention group (13-24 weeks after randomisation). Interpretation Our study does not provide evidence that patients with Guillain-Barre syndrome with a poor prognosis benefit from a second intravenous immunoglobulin course; moreover, it entails a risk of serious adverse events. Therefore, a second intravenous immunoglobulin course should not be considered for treatment of Guillain-Barre syndrome because of a poor prognosis. The results indicate the need for treatment trials with other immune modulators in patients severely affected by Guillain-Barre syndrome. Funding Prinses Beatrix Spierfonds and Sanquin Plasma Products. Copyright (C) 2021 Elsevier Ltd. All rights reserved

    Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

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    To identify novel genes associated with ALS, we undertook two lines of investigation. We carried out a genome-wide association study comparing 20,806 ALS cases and 59,804 controls. Independently, we performed a rare variant burden analysis comparing 1,138 index familial ALS cases and 19,494 controls. Through both approaches, we identified kinesin family member 5A (KIF5A) as a novel gene associated with ALS. Interestingly, mutations predominantly in the N-terminal motor domain of KIF5A are causative for two neurodegenerative diseases: hereditary spastic paraplegia (SPG10) and Charcot-Marie-Tooth type 2 (CMT2). In contrast, ALS-associated mutations are primarily located at the C-terminal cargo-binding tail domain and patients harboring loss-of-function mutations displayed an extended survival relative to typical ALS cases. Taken together, these results broaden the phenotype spectrum resulting from mutations in KIF5A and strengthen the role of cytoskeletal defects in the pathogenesis of ALS.Peer reviewe

    Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

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    Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe

    The role of urban green infrastructure in mitigating land surface temperature in Bobo-Dioulasso, Burkina Faso

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    Green infrastructure in developed countries has been used as a climate change adaptation strategy to lower increased temperatures in cities. But, the use of green infrastructure to provide ecosystem services and increase resilience is largely overlooked in climate change and urban policies in the developing world. This study analyzed the role of urbanization and green infrastructure on urban surface temperatures in Bobo-Dioulasso, Burkina Faso, in sub-Saharan Africa. We use available geospatial data and techniques to spatially and temporally explore urbanization and land surface temperatures (LSTs) over 20 years. The effect of specific green infrastructure areas in the city on LSTs was also analyzed. Results show increased urbanization rates and increased temperature trends across time and space. But, LST in green infrastructure areas was indeed lower than adjacent impervious, urbanized areas. Seasonal phenological differences due to rainfall patterns, available planting space, and site limitations should be accounted for to maximize temperature reduction benefits. We discuss an approach on how study findings and urban and peri-urban agriculture and forestry are being used for policy uptake and formulation in the field of climate change, food security, and urbanization by the municipal government in this city in Burkina Faso.Center for Territorial Studies, Faculty of Agricultural Sciences, National University of Rosario, Parque Villarino, C. C. 14, S2125ZAA Zavalla, Santa Fe, ArgentinaSchool of Forest Resources and Conservation, University of Florida-IFAS, 361 Newins-Ziegler Hall, PO Box 110410, Gainesville, FL 32611, USARUAF Foundation-International Network of Resource Centres on Urban Agriculture and Food Security, Kastanjelaan 5, 3833 AN Leusden, The Netherland

    A Spatially Explicit Method to Assess the Economic Suitability of a Forest Road Network for Timber Harvest in Steep Terrain

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    Despite relatively high road density in the forests of Switzerland, a large percentage of that road network does not fulfill best practice requirements. Before upgrading or rebuilding the road network, harvesting planners must first determine which areas have insufficient access. Traditional assessment methods tend to only report specific values such as road density. However, those values do not identify the exact parcels or areas that are inaccessible. Here, we present a model that assesses the economic suitability of each timbered parcel for wood-harvesting operations, including tree-felling and processing, and off- and on-road transport (hauling), based on the existing road network. The entire wood supply chain from forest (standing trees) to a virtual pile at the border of the planning unit was captured. This method was particularly designed for steep terrain and was tested in the Canton of Grisons in Switzerland. Compared with classical approaches, such as the road density concept, which only deliver average values, this new method enables planners to assess the development of a road network in a spatially explicit manner and to easily identify the reason and the location of shortcomings in the road network. Moreover, while other related spatially explicit approaches focus only on harvesting operations, the assessment method proposed here also includes limitations (road standards) of the road network
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